• Persistent and continuous coughing • Coughing up blood
• Hoarseness
• Shortness of breath, wheezing
• Difficulty breathing
• Fatigue
• Chest, back or shoulder pain, especially during deep breaths
• Face and neck swelling
• Unexplained weight loss, loss of appetite
• Clubbing of the fingers (uncommon)
• Relentless bronchitis
• Weakness
• Headaches
• Bone fractures
• Bleeding, blood clots
• Depression
